The two WHO formulations had a virus reduction factor of >3.8, while the modified versions had a reduction factor of ≥5.9.īoth ethanol and 2-propanol reduced virus to background levels in 30 seconds, with reduction factors of 4.8 to ≥5.9, and a concentration of ≥30% of either ingredient was effective in killing SARS-CoV-2, the virus that causes COVID-19. They found that all sanitizer formulations and dilutions of 40% or more killed the coronavirus and reduced the virus to background levels within 30 seconds. They tested virus activity after 30 seconds of exposure to the hand sanitizer using a suspension of 1 part virus, 1 part organic material, and 8 parts disinfectant solution in different concentrations. The Swiss and German researchers also tested dilutions of the alcohols ethanol and 2-propanol, the active ingredients of hand sanitizers on the market. The modified versions used in this study consisted of (1) 80% ethanol, 0.725% glycerol, and 0.125% hydrogen peroxide and (2) 75% 2-propanol, 0.725% glycerol, and 0.125% hydrogen peroxide. In response, Suchomel and colleagues, who were not involved in today's study, modified the formulations by adding more ethanol or isopropanol and using less glycerol after finding that glycerol reduced their effectiveness. However, these formulations failed to meet the effectiveness requirements of European Norm 1500, which measures how much live bacteria remain on contaminated fingertips after using hand sanitizer. The WHO recommends two formulas: (1) 80% ethanol, 1.45% glycerol, and 0.125% hydrogen peroxide and (2) 75% 2-propanol, 1.45% glycerol, and 0.125% hydrogen peroxide. ![]() In the hand sanitizer study, the researchers evaluated the effectiveness of different concentrations of two WHO-recommended and two modified hand sanitizer formulations on COVID-19 virus. Commercially available sanitizers kill coronavirus In a study today in Emerging Infectious Diseases, Swiss and German researchers found that alcohol-based hand sanitizers recommended by the World Health Organization (WHO) are effective in killing the novel coronavirus.Īnd a study today in the Annals of Internal Medicine with important COVID-19 ramifications found that 70.2% of 6,512 electronic consultations (e-consults) made by 1,096 referring clinicians to 121 specialists were appropriate.
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